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000958969 020__ $$a9783030527808$$q(electronic book)
000958969 020__ $$a3030527808$$q(electronic book)
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000958969 0247_ $$a10.1007/978-3-030-52780-8$$2doi
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000958969 24500 $$aBasic epithelial ion transport principles and function :$$bion channels and transporters of epithelia in health and disease.$$nVol. 1 /$$cKirk L. Hamilton, Daniel C. Devor, editors.
000958969 24630 $$aIon channels and transporters of epithelia in health and disease
000958969 250__ $$aSecond edition.
000958969 264_1 $$aCham :$$bSpringer,$$c[2020]
000958969 300__ $$a1 online resource.
000958969 336__ $$atext$$btxt$$2rdacontent
000958969 337__ $$acomputer$$bc$$2rdamedia
000958969 338__ $$aonline resource$$bcr$$2rdacarrier
000958969 4901_ $$aPhysiology in health and disease,$$x2625-252X
000958969 504__ $$aReferences.
000958969 5050_ $$a1. Techniques in Epithelial Transport -- 2. Understanding Transepithelial Current Measurements -- 3. Mathematical Modeling of Epithelial Ion Transport -- 4. Rationale of Epithelia Transport -- 5. Establishment of Epithelial Polarity -- 6. Molecular Mechanisms of Apical and Basolateral Sorting in Polarized Epithelial Cells -- 7. Membrane Protein Folding and Structure -- 8. Epithelial Ion Channel Folding and ER Associated Degradation (ERAD) -- 9. Fundamentals of Epithelial Cl- Transport -- 10. Fundamentals of Epithelial Na+ Absorption -- 11. Physiologic Influences of Transepithelial K+ Secretion -- 12. Volume Regulation in Epithelia -- 13. Fundamentals of Bicarbonate Secretion in Epithelia -- 14. Sexual Dimorphism of Epithelial Ion Channels -- 15. Non-coding RNA-Dependent Regulation of Channels/Transporters.
000958969 506__ $$aAccess limited to authorized users.
000958969 520__ $$aThis book discusses unique ion channels and transporters that are located within epithelial tissues of various organs including the kidney, intestine, pancreas and respiratory tract. As the authors show, these channels and transporters play crucial roles in transepithelial ion and fluid transport across epithelia and their contribution to maintaining homeostasis. Readers will be introduced to the fundamentals of ion transport in terms of function, modelling, regulation, structure and pharmacology. This is the first of three volumes highlighting the importance of epithelial ion channels and transporters in basic physiology and pathophysiology of human diseases. This volume focuses on basic fundamentals of epithelial transport physiology. There is a range of chapters dedicated to specific aspects of epithelial ion transport and cell function. Accordingly, the authors discuss techniques used to determine epithelial function, principles of epithelia transport, polarization of epithelial cells, mathematical modelling of epithelial ion transport, protein folding of ion channels, degradation epithelial ion channels, fundamentals of epithelial sodium, potassium and chloride transport, fundamentals of bicarbonate secretion, volume regulation, and microRNA regulation of epithelial channels and transporters. Given its scope, Volume 1 offers a valuable resource for physiology students, scientists and clinicians alike.
000958969 588__ $$aOnline resource; title from PDF title page (SpringerLink, viewed February 8, 2021).
000958969 650_0 $$aIon channels.
000958969 650_0 $$aEpithelium.
000958969 650_0 $$aHuman physiology.
000958969 650_0 $$aMolecular biology.
000958969 650_0 $$aProteins.
000958969 650_0 $$aCell membranes.
000958969 7001_ $$aHamilton, Kirk L.,$$d1953-$$eeditor.
000958969 7001_ $$aDevor, Daniel C.,$$d1961-$$eeditor.
000958969 77608 $$iPrint version: $$z9783030527822
000958969 830_0 $$aPhysiology in health and disease,$$x2625-252X
000958969 852__ $$bebk
000958969 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-3-030-52780-8$$zOnline Access$$91397441.1
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000958969 980__ $$aBIB
000958969 982__ $$aEbook
000958969 983__ $$aOnline
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