000959103 000__ 02524cam\a2200445M\\4500 000959103 001__ 959103 000959103 005__ 20230306152638.0 000959103 006__ m\\\\\o\\d\\\\\\\\ 000959103 007__ cr\un\nnnunnun 000959103 008__ 210126s2020\\\\xx\\\\\\o\\\\\0||\0\eng\d 000959103 020__ $$a9789811558078$$q(electronic book) 000959103 020__ $$a9811558078$$q(electronic book) 000959103 020__ $$z981155806X 000959103 020__ $$z9789811558061 000959103 035__ $$aSP(OCoLC)on1239998258 000959103 035__ $$aSP(OCoLC)1239998258 000959103 040__ $$aYDX$$beng$$cYDX$$dDKU 000959103 049__ $$aISEA 000959103 050_4 $$aQP110.G45 000959103 08204 $$a611.01816$$223 000959103 1001_ $$aKIM, CHEORL-HO. 000959103 24510 $$aGLYCOSPHINGOLIPIDS SIGNALING. 000959103 260__ $$a[S.l.] :$$bSPRINGER VERLAG, SINGAPOR,$$c2020. 000959103 300__ $$a1 online resource 000959103 336__ $$atext$$btxt$$2rdacontent 000959103 337__ $$acomputer$$bc$$2rdamedia 000959103 338__ $$aonline resource$$bcr$$2rdacarrier 000959103 5050_ $$a1. Glycosphingolipids (GSLs) -- 2. Mammal GSL synthesis via ER and Golgi network -- 3. The GSL dependent signaling -- 4. Viral protein interaction with host cells GSLs -- 5. Bacterial toxin protein interaction with host cells GSL -- 6. GSL signaling regulation. 000959103 506__ $$aAccess limited to authorized users. 000959103 520__ $$aThis book presents the latest knowledge and the most recent research results on glycosphingolipid (GSL)-mediated signaling. GSLs are important constituents of the plasma membrane that exert their distinct functions through binding to certain functional proteins. They play a role in various human diseases and also function as human alloantigens. Cellular GSLs are associated with many biological functions such as cellular oncotransformation, phenotype change, neuronal or embryonic development, regulation of cell division, cell-cell interaction, cell attachment, adhesion, and motility, and intracellular signaling via protein-carbohydrate or carbohydrate-carbohydrate interactions. This book opens by providing the key background on GSL glycan-receptor interactions and mammalian GSL synthesis. Up-to-date information is then presented on all aspects of GSL-dependent signaling. Viral protein and bacterial toxin protein interactions with host cell GSLs are examined in depth, and the concluding chapter is devoted to signaling regulation. The book should assist in the further development of new strategies against emerging infectious agents and intractable diseases. 000959103 650_0 $$aGene expression. 000959103 650_0 $$aCancer$$xResearch. 000959103 650_0 $$aGenetics. 000959103 650_0 $$aBiochemistry. 000959103 650_0 $$aCell membranes. 000959103 77608 $$iPrint version:$$z981155806X$$z9789811558061$$w(OCoLC)1152457929 000959103 852__ $$bebk 000959103 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-981-15-5807-8$$zOnline Access$$91397441.1 000959103 909CO $$ooai:library.usi.edu:959103$$pGLOBAL_SET 000959103 980__ $$aEBOOK 000959103 980__ $$aBIB 000959103 982__ $$aEbook 000959103 983__ $$aOnline 000959103 994__ $$a92$$bISE