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000959652 0247_ $$a10.1007/978-981-33-4033-6$$2doi
000959652 035__ $$aSP(OCoLC)on1237409429
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000959652 050_4 $$aQP33.6.M36
000959652 08204 $$a612.001/5118$$223
000959652 1001_ $$aChen, Shangbin,$$eauthor.
000959652 24510 $$aQuantitative physiology :$$bsystems approach /$$cShangbin Chen, Alexey Zaikin.
000959652 264_1 $$aSingapore :$$bSpringer ;$$a[China] :$$bHuazhong University of Science and Technology Press,$$c[2020]
000959652 300__ $$a1 online resource (246 pages)
000959652 336__ $$atext$$btxt$$2rdacontent
000959652 337__ $$acomputer$$bc$$2rdamedia
000959652 338__ $$aonline resource$$bcr$$2rdacarrier
000959652 504__ $$aIncludes bibliographical references.
000959652 5050_ $$aIntroduction of Quantitative Physiology -- Systems and Modelling -- Relevant Resources -- Modelling Gene Expression -- Bone and Body Mechanics -- Blood Dynamics -- Metabolic Network -- Systems pharmacology -- Calcium Signalling -- Modelling Neural Activity -- Cortical Spreading Depression (CSD) -- Heart Physiome -- Constructing genetic intelligence -- Brain Project.
000959652 506__ $$aAccess limited to authorized users.
000959652 520__ $$aStephen Hawking says that the 21st century will be the century of complexity and indeed now systems biology or medicine means dealing with complexity. Both the genome and physiome have emerged in studying complex physiological systems. Computational and mathematical modeling has been regarded as an efficient tool to boost the understanding about living systems in normal or pathophysiological states. Covering applied methodology, basic case studies and complex applications, this volume provides researchers with an overview of modeling and computational studies of physiology (i.e. quantitative physiology), which is becoming an increasingly important branch of systems biology. This book aims to build multi-scale models to investigate functions in living systems and explain how biomolecules, cells, organs, organ systems and organisms carry out the chemical or physical functions. Some of the models addressed are related to gene expression, calcium signalling, neural activity, blood dynamics and bone mechanics. Combining theory and practice, with extensive use of MATLAB, this book is designed to establish a paradigm for quantitative physiology by integrating biology, mathematics, physics and informatics etc. To benefit from this book, the readers are expected to have a background in general physiology and mathematics.
000959652 588__ $$aDescription based upon print version of record.
000959652 650_0 $$aPhysiology$$xMathematical models.
000959652 655_0 $$aElectronic books.
000959652 7001_ $$aZaikin, Alexey,$$eauthor.
000959652 77608 $$iPrint version:$$aChen, Shangbin$$tQuantitative Physiology$$dSingapore : Springer Singapore Pte. Limited,c2021$$z9789813340329
000959652 852__ $$bebk
000959652 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-981-33-4033-6$$zOnline Access$$91397441.1
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000959652 980__ $$aEBOOK
000959652 980__ $$aBIB
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000959652 983__ $$aOnline
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