Translational research in breast cancer / Dong-Young Noh, Wonshik Han, Masakazu Toi, editors.
Noh, Dong-Young, editor.; Han, Wonshik, editor.; Toi, Masakazu, editor.
2021
RC280.B8
Available Online

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Title Translational research in breast cancer / Dong-Young Noh, Wonshik Han, Masakazu Toi, editors.
ISBN 9789813296206 (electronic bk.)
9813296208 (electronic bk.)
9789813296190 (print)
9813296194
DOI https://doi.org/10.1007/978-981-32-9620-6
Published Singapore : Springer, [2021]
Language English
Description 1 online resource (ix, 630 pages) : illustrations (some color)
Other Standard Identifiers 10.1007/978-981-32-9620-6 doi
Call Number RC280.B8
Dewey Decimal Classification 616.99/4490072
Summary This book describes recent advances in translational research in breast cancer and presents emerging applications of this research that promise to have meaningful impacts on diagnosis and treatment. It introduces ideas and materials derived from the clinic that have been brought to "the bench" for basic research, as well as findings that have been applied back to "the bedside". Detailed attention is devoted to breast cancer biology and cell signaling pathways and to cancer stem cell and tumor heterogeneity in breast cancer. Various patient-derived research models are discussed, and a further focus is the role of biomarkers in precision medicine for breast cancer patients. Next-generation clinical research receives detailed attention, addressing the increasingly important role of big data in breast cancer research and a wide range of other emerging developments. An entire section is also devoted to the management of women with high-risk breast cancer. Translational Research in Breast Cancer will help clinicians and scientists to optimize their collaboration in order to achieve the common goal of conquering breast cancer
Access Note Access limited to authorized users.
Source of Description Online resource; title from PDF title page (SpringerLink, viewed May 20, 2021).
Added Author Noh, Dong-Young, editor.
Han, Wonshik, editor.
Toi, Masakazu, editor.
Series Advances in experimental medicine and biology ; v. 1187. 0065-2598
Available in Other Form Print version: 9789813296190
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Record Appears in Online Resources > Ebooks
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Part I. Introduction
Chapter 1. Translational Research in Surgical Oncology: Introduction and My Own Experience as a Surgeon-Scientist
Part II. Breast Cancer Biology and Cell Signaling Pathways
Chapter 2. Phospholipase Signaling in Breast Cancer
Chapter 3. HER2 Signaling in Breast Cancer
Chapter 4. Ras Signaling in Breast Cancer
Chapter 5. Epigenetic Regulation in Breast Cancer
Chapter 6. Role of tRNAs in Breast Cancer Regulation
Chapter 7. Fusion Genes in Breast Cancer
Chapter 8. DNA Damage Repair Inhibitor for Breast Cancer Treatment
Part III. Cancer Stem Cell and Tumor Heterogeneity in Breast Cancer
Chapter 9. Breast Cancer Metastasis
Chapter 10. Single Cell Genomics for Tumor Heterogeneity
Chapter 11. Advances in Tumor Sampling and Sequencing in Breast Cancer and their Application in Precision Diagnostics and Therapeutics
Chapter 12. Cancer Stem Cell in Immune Microenvironment
Chapter 13. Theranostics for Breast Cancer Stem Cells
Chapter 14. Patient-Derived Xenograft Models in Breast Cancer Research
Part IV Biomarkers for Precision Medicine in Breast Cancer Patients
Chapter 15. Proteomic Interrogation in Cancer Biomarker
Chapter 16. Next-Generation Sequencing-Based Biomarkers in Breast Cancer
Chapter 17. Liquid Biopsy in Breast Cancer: Circulating Tumor Cells and Circulating Tumor DNA
Chapter 18. Current Biomarkers for Precision Medicine in Breast Cancer
Chapter 19. The Potential Predictors in Chemotherapy Sensitivity
Chapter 20. Hormone Resistance
Part V. Managing High Risk Women
Chapter 21. High-Risk Population Based on BC Risk Factors
Chapter 22. Breast Cancer-Related Low Penetrance Genes
Chapter 23. Rare Coding Variants Associated with Breast Cancer
Chapter 24. Multigene Panel Testing for Hereditary Cancer and Genetic Counseling
Chapter 25. BRCA and Breast Cancer-Related High-Penetrance Genes
Part VI. Next Generation Clinical Research
Chapter 26. Clinical Databases for Breast Cancer Research
Chapter 27. Care for Breast Cancer Survivors
Chapter 28. Considerations in Oncoplastic Surgery
Chapter 29. Diet Before and After Breast Cancer
Chapter 30. Current Trends in and Indications for Endoscopy-Assisted Breast Surgery for Breast Cancer
Chapter 31. Minimal Invasive and Individualizing Management of the Axillary Nodes
Chapter 32. Malignant Phyllodes of Breast
Chapter 33. Next-Generation Clinical Trials and Research with Successful Collaborations
Part VII. Epilogue
Chapter 34. Transformation of the Patient and Society: A Patient Survivors' Group and Breast Cancer Awareness Campaign.

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