Three dimensional human organotypic models for biomedical research / Fabio Bagnoli, Rino Rappuoli, editors.
Bagnoli, Fabio, editor.; Rappuoli, Rino, editor.
2021
R853.T58 T57 2021
Available Online

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Title
Three dimensional human organotypic models for biomedical research / Fabio Bagnoli, Rino Rappuoli, editors.
ISBN
9783030624521 (electronic bk.)
3030624528 (electronic bk.)
9783030624538 (print)
3030624536
9783030624545 (print)
3030624544
9783030624514
303062451X
DOI
https://doi.org/10.1007/978-3-030-62452-1
Published
Cham : Springer, [2021]
Copyright
©2021
Language
English
Description
1 online resource : illustrations (chiefly color)
Item Number
10.1007/978-3-030-62452-1 doi
Call Number
R853.T58 T57 2021
Dewey Decimal Classification
610.72/4
Summary
This edited volume discusses the application of very diverse human organotypic models in major areas of biomedical research. The authors lay a main focus on infectious diseases, cancer, allergies, as well as drug/vaccine discovery and toxicology studies. Representing a valid alternative to laboratory animals, these models are relevant for most areas of translational research. As the contemporary research shows, many human tissues can today be cultivated in vitro and used for several research objectives. This book provides an unprecedented overview of recent developments in an exciting field of research methodology. It is a reference guide for scientists in both academia and industry. Readers can update their knowledge and get hands-on recommendations on how to set up an organotypic model in their lab. Chapters 'Progress on Reconstructed Human Skin Models for Allergy Research and Identifying Contact Sensitizers' and 'Human Organotypic Models for Anti-infective Research' of this book are available open access under a CC BY 4.0 license at link.springer.com.
Bibliography, etc. Note
Includes bibliographical references.
Access Note
Access limited to authorized users.
Digital File Characteristics
text file
PDF
Source of Description
Online resource; title from PDF title page (SpringerLink, viewed June 11, 2021).
Added Author
Bagnoli, Fabio, editor.
Rappuoli, Rino, editor.
Series
Current topics in microbiology and immunology ; 430. 0070-217X
Available in Other Form
Three dimensional human organotypic models for biomedical research.
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Introduction: Rationale of using skin models in research
Skin anatomy (human and animals for experimental research)
In vivo skin models
In vitro human skin models (Skin equivalents vs skin explants)
Human skin models for studying cutaneous infections
Skin animal models for pharmacological research
Human skin models for pharmacological research
Human skin models for allergological research
Human skin models for cancer research
Human skin models for vaccine research.

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