Epitranscriptomics / Stefan Jurga, Jan Barciszewski, editors.
Jurga, Stefan, editor.; Barciszewski, Jan, editor.
2021
QH450.2 .E65 2021
Available Online

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Title Epitranscriptomics / Stefan Jurga, Jan Barciszewski, editors.
ISBN 9783030716127 (electronic bk.)
3030716120 (electronic bk.)
3030716112
9783030716110
DOI https://doi.org/10.1007/978-3-030-71612-7
Published Cham, Switzerland : Springer, 2021.
Language English
Description 1 online resource
Other Standard Identifiers 10.1007/978-3-030-71612-7 doi
Call Number QH450.2 .E65 2021
Dewey Decimal Classification 572.8/845
Summary This book reviews a novel and exciting ld of cellular and molecular biology called epitranscriptomics, which focuses on changes in an organism's cells resulting from the posttranscriptional modification of cellular RNA. RNA-binding proteins (RBPs) play a crucial role in these posttranscriptional modifications and also support several cellular processes necessary for maintaining RNA homeostasis. Exploring the mechanisms underlying RNA modifications and RBP function is an emerging area of biomedical research, taking the study of gene regulation a step beyond epigenetics. This book reveals that the RNA molecule is not just an information-carrying molecule with some secondary structures. Accordingly, how RNA is modified, regulated, packaged, and controlled is an important aspect. Leading experts address questions such as where the over 170 distinct posttranscriptional RNA modifications are located on the genome, what percentage of mRNAs and noncoding RNAs these modifications include, and how an RNA modification impacts a person's biology. In closing, the book reviews the role of RNA modifications and RBPs in a variety of diseases and their pathogenesis. Addressing some of the most exciting challenges in epitranscriptomics, this book provides a valuable and engaging resource for researchers in academia and industry studying the phenomena of RNA modification.
Access Note Access limited to authorized users.
Source of Description Online resource; title from PDF title page (SpringerLink, viewed August 11, 2021).
Added Author Jurga, Stefan, editor.
Barciszewski, Jan, editor.
Series RNA technologies ; v. 12. 2197-9731
Available in Other Form Print version: 9783030716110
Linked Resources Online Access
Record Appears in Online Resources > Ebooks
All Resources
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