The 'big four' snakes of India : venom composition, pharmacological properties and treatment of envenomation / Ashis K. Mukherjee.
Mukherjee, Ashis K., author.
2021
QP632.V46
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Title
The 'big four' snakes of India : venom composition, pharmacological properties and treatment of envenomation / Ashis K. Mukherjee.
Author
Mukherjee, Ashis K., author.
ISBN
9789811628962 (electronic bk.)
9811628963 (electronic bk.)
9811628955
9789811628955
DOI
https://doi.org/10.1007/978-981-16-2896-2
Published
Singapore : Springer, 2021.
Language
English
Description
1 online resource
Item Number
10.1007/978-981-16-2896-2 doi
Call Number
QP632.V46
Dewey Decimal Classification
615.9/42
Summary
This book provides detailed and updated knowledge about medically important Big Four venomous snakes of India (Indian spectacled cobra, Indian common krait, Indian Russells viper, and Indian saw-scaled viper). This book essentially covers the snakebite problem in the world with particular reference to Asia and India. It discusses the evolution and systematics of venomous snakes, emphasizing Big Four venomous snakes of India; the evolution and composition of venoms determined by traditional biochemical and modern proteomic analyses. It also describes the pharmacological properties of enzymatic and non-enzymatic toxins of Big Four venomous snakes of India. Different chapters discuss exciting topics such as species-specific and geographical differences in venom composition and its impact on pathophysiology and clinical manifestations of snakebite envenomation in India, biomedical application of Indian snake venom toxins; production and quality assessment of commercial antivenom, prevention, and treatment of snakebite in India, adverse effects of antivenom including strategies to combat antivenom reactions inpatient. This book caters to toxinologists, pharmacologists, zoologists, antivenom manufacturers, biochemists, clinicians, evolutionary biologists, herpetologists, and informed non-specialists interested to know about the Indian snake venoms.
Bibliography, etc. Note
References-4: Indian Spectacled Cobra (Naja naja)-4.1 Taxonomic Classification of the Indian Spectacled Cobra (Naja naja)-4.2 Characteristic Features of the Indian Spectacled Cobra-4.3 Geographical Distribution and Reproduction of the Indian Spectacled Cobra-4.4 Biochemical Composition of the Indian Spectacled Cobra Venom-4.5 Biochemical and Proteomic Analyses to Demonstrate the Geographical Differences in Venom Composition of Indian Spectacled C ...-4.6 Genomic and Transcriptomic Analyses of Indian Spectacled Cobra Venom Toxins.
Includes bibliographical references.
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Access limited to authorized users.
Digital File Characteristics
text file
PDF
Source of Description
Online resource; title from PDF title page (SpringerLink, viewed September 13, 2021).
Available in Other Form
'big four' snakes of India.
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Intro
Preface
Contents
About the Author
1: Introduction
1.1 A Glimpse of the Venomous Snakes of India
1.2 The Concept of the ``Big Four ́́and Non-``Big Four ́́Medically Important Venomous Snakes of India
1.3 Medical Aspects of Snakebite: The Snakebite Problem
1.3.1 Snakebite in Developed Countries
1.3.2 Epidemiology of Snakebite in Asia
1.3.3 Epidemiology of Snakebite in India
1.4 Key Issues Pertaining to Snakebite in India
References
2: Evolution of Snakes and Systematics of the ``Big Four ́́Venomous Snakes of India
2.1 Evolution of Snakes

2.2 Studies of the Genomics, Phenomics, and Fossil Record Show the Origin and Evolution of Snakes
2.3 Studies on the Genomic Regression of Claw Keratin, Taste Receptors, and Light-Associated Genes and the Evolutionary Origin...
2.4 Skull Evolution and the Ecological Origin of Snakes
2.5 Systematics of the ``Big Four ́́Venomous Snakes of India
2.6 The ``Big Four ́́Venomous Snakes of India Represent the Advanced Group of Snakes
2.6.1 Family Elapidae
2.6.1.1 Genus Bungarus (Kraits)
2.6.1.2 Genus Naja (Cobras)
2.6.2 Family Viperidae
2.6.2.1 Genus Daboia

2.6.2.2 Genus Echis
References
3: Snake Venom: Composition, Function, and Biomedical Applications
3.1 The Venom Gland and Venom Delivery Apparatus in the Viperidae and Elapidae Families of Snakes
3.2 Comprehensive Review of the Venom Composition of the ``Big Four ́́Venomous Snakes of India
3.2.1 Enzymatic Toxins of the ``Big Four ́́Snake Venoms
3.2.2 Nonenzymatic Toxins in the ``Big Four ́́Snake Venoms
3.2.3 Nonprotein Components of Snake Venom
3.3 Variation in Snake Venom Composition and Its Impact on the Pathogenesis of Snakebite and Antivenom Treatment

3.4 Evolution of Genes for the Toxins in Snake Venom
3.4.1 Toxicofera Hypothesis
3.4.2 Independent Origin Hypothesis
3.5 Mechanism of the Evolution and Diversification of Venom Proteins
3.5.1 Accelerated Evolution of Venom Protein Genes
3.5.2 Selection Pressure for Rapid Adaptive Evolution
3.5.3 Diet and Snake Venom Evolution
3.6 Biological Functions of Venom
3.6.1 Prey-Specific Venom Toxicity
3.6.2 Immobilization and Predigestion of Prey
3.6.3 Prey Re-localization
3.7 Indian Snake Venom Proteins: A Treasure House of Drug Prototypes and Diagnostic Tool

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