Antimalarial natural products / A. Douglas Kinghorn, Heinz Falk, Simon Gibbons, Yoshinori Asakawa, Ji-Kai Liu, Verena M. Dirsch, editors ; by David G. I. Kingston and Maria Belen Cassera.
2022
RC159.A5
Linked e-resources
Linked Resource
Online Access
Concurrent users
Unlimited
Authorized users
Authorized users
Document Delivery Supplied
Can lend chapters, not whole ebooks
Details
Title
Antimalarial natural products / A. Douglas Kinghorn, Heinz Falk, Simon Gibbons, Yoshinori Asakawa, Ji-Kai Liu, Verena M. Dirsch, editors ; by David G. I. Kingston and Maria Belen Cassera.
ISBN
9783030898731 (electronic bk.)
3030898733 (electronic bk.)
9783030898724 (print)
3030898725
3030898733 (electronic bk.)
9783030898724 (print)
3030898725
Published
Cham, Switzerland : Springer, 2022.
Language
English
Description
1 online resource (ix, 106 pages) : illustrations (some color).
Item Number
10.1007/978-3-030-89873-1 doi
Call Number
RC159.A5
Dewey Decimal Classification
616.9/362061
Summary
This volume begins with a short history of malaria and follows with a summary of its biology. It then traces the fascinating history of the discovery of quinine for malaria treatment, and then describes quinine's biosynthesis, its mechanism of action, and its clinical use, concluding with a discussion of synthetic antimalarial agents based on quinine's structure. It also covers the discovery of artemisinin and its development as the source of the most effective current antimalarial drug, including summaries of its synthesis and biosynthesis, its mechanism of action, and its clinical use and resistance. A short discussion of other clinically used antimalarial natural products leads to a detailed treatment of additional natural products with significant antiplasmodial activity, classified by compound type. Although the search for new antimalarial natural products from Nature's combinatorial library is challenging, it is very likely to yield new antimalarial drugs. This book thus ends by identifying ten natural products with development potential as clinical antimalarial agents.
Access Note
Access limited to authorized users.
Source of Description
Online resource; title from PDF title page (SpringerLink, viewed January 7, 2022).
Added Author
Cassera, Maria Belen, author.
Kinghorn, A. Douglas, editor.
Falk, Heinz, 1939- editor.
Gibbons, Simon (Professor of medicinal phytochemistry), editor.
Asakawa, Yoshinori, editor.
Liu, Ji-Kai, editor.
Dirsch, Verena M. editor.
Kinghorn, A. Douglas, editor.
Falk, Heinz, 1939- editor.
Gibbons, Simon (Professor of medicinal phytochemistry), editor.
Asakawa, Yoshinori, editor.
Liu, Ji-Kai, editor.
Dirsch, Verena M. editor.
Series
Progress in the chemistry of organic natural products (2011) ; 117. 2192-4309
Available in Other Form
Print version: 9783030898724
Linked Resources
Online Access
Record Appears in
Online Resources > Ebooks
All Resources
All Resources