Purifying and indexing technology for nucleic acids-based next generation storage medium / Hansol Choi.
2023
TA164
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Online Access
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Unlimited
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Authorized users
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Can lend chapters, not whole ebooks
Details
Title
Purifying and indexing technology for nucleic acids-based next generation storage medium / Hansol Choi.
Author
Choi, Hansol, author.
ISBN
9789811942747 (electronic bk.)
9811942749 (electronic bk.)
9789811942730
9811942749 (electronic bk.)
9789811942730
Published
Singapore : Springer, [2023]
Language
English
Description
1 online resource (xv, 42 pages) : illustrations (some color).
Item Number
10.1007/978-981-19-4274-7 doi
Call Number
TA164
Dewey Decimal Classification
570.28
Summary
This book introduces novel purification technology for the complex oligonucleotide libraries. Since the concept of synthesizing oligonucleotides (oligos) has been proposed, research fields such as nucleic acid-based therapies (CRISPR-Cas9, DNA/RNA vaccines, RNAi), synthetic biology, protein engineering, and DNA-based data storage have bloomed. The COVID-19 pandemic underscores the potential of nucleic acid-based technologies, such as vaccines or diagnostics. As they emerge as the most promising weapons against the current pandemic, increasing need for highly accessible nucleic acid purification technologies is expected. To meet this demand, an oligo purification technology that can be applied to complex oligo libraries and can purify oligos with single-base resolution is developed. In addition, the purification technology can be applied to highly complex oligo libraries of different lengths, enabling the simultaneous purification of complex oligo libraries with different lengths. The proposed technology can be easily accessed by users and would help accelerate numerous research fields that utilize oligos as fundamental building blocks.
Note
"Doctoral Thesis accepted by Seoul National University, Seoul, South Korea."
Bibliography, etc. Note
Includes bibliographical references.
Access Note
Access limited to authorized users.
Source of Description
Online resource; title from PDF title page (SpringerLink, viewed August 22, 2022).
Series
Springer theses, 2190-5061
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Table of Contents
Introduction
Synthetic Nucleic Acids Storage
Highly Parallel Oligonucleotide Libraries Purification
Conclusion and Discussion.
Synthetic Nucleic Acids Storage
Highly Parallel Oligonucleotide Libraries Purification
Conclusion and Discussion.