Therapeutic applications of dopamine D3 receptor function : new insight after 30 years of research / Isabelle Boileau, Ginetta Collo, editors.
Boileau, Isabelle, editor.; Collo, Ginetta, editor.
2023
RM315
Available Online

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Title Therapeutic applications of dopamine D3 receptor function : new insight after 30 years of research / Isabelle Boileau, Ginetta Collo, editors.
ISBN 9783031230585 (electronic bk.)
3031230582 (electronic bk.)
9783031230578
3031230574
DOI https://doi.org/10.1007/978-3-031-23058-5
Published Cham : Springer, [2023]
Copyright ©2023
Language English
Description 1 online resource (viii, 275 pages) : illustrations.
Item Number 10.1007/978-3-031-23058-5 doi
Call Number RM315
Dewey Decimal Classification 615.7/8
Summary The CTBN volume Therapeutic Applications of Dopamine D3 Receptor Function reviews the state of the knowledge on the dopamine D3 receptor and its role in human behavior and disease (i.e.: neuropsychiatric illnesses including schizophrenia, mood disorders, Parkinsons disease, restless legs syndrome, addictions and substance use disorders). The volume is written by leading experts across multidisciplinary areas (imaging, biobehavioral testing and clinical trials, preclinical models / molecular pharmacology) converging on the therapeutic implications / potential of the D3 receptor. The D3 dopamine receptor is a member of the D2-like family of G protein-coupled receptors. It was cloned and characterized almost 25 years ago. A key feature of the D3 dopamine receptor system, which has attracted considerable attention, is its anatomical localization remarkably restricted to the limbic circuitry. This has spurred the hypothesis that D3 involvement could contribute to the pathophysiology of neuropsychiatric disorders (or to some features of neuropsychiatric disorders), including but not limited to psychosis, addictions and substance abuse, mood and movement disorders.
Access Note Access limited to authorized users.
Source of Description Online resource; title from PDF title page (SpringerLink, viewed January 12, 2023).
Added Author Boileau, Isabelle, editor.
Collo, Ginetta, editor.
Series Current topics in behavioral neurosciences ; 60. 1866-3389
Available in Other Form Print version: 9783031230578
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Preface
A Historic Review of the D3 Dopamine System from D3 Cloning to Clinical Trials in Schizophrenia and Drug Addiction
Location, Location, Location: The Expression of D3 Dopamine Receptors in the Nervous System
Recent Advances in Dopamine D3 Receptor Heterodimers: Focus on Dopamine D3 and D1 Receptor-Receptor Interaction and Striatal Function
Involvement of DA D3 Receptor and Mitochondrial Functions in Structural Neuroplasticity of the Emotional Brain Circuits: Possible Role in Depression
Dopamine D3 Receptor in Parkinson Disease: A Prognosis Biomarker and an Intervention Target
Dopamine D3 Receptors: A Potential Target to Treat Motivational Deficits in Parkinsons Disease
Therapeutic Challenges of Cognitive Dysfunctions in Neuropsychiatric Disorders: Focus on the Dopamine D3 Receptor
Dopamine D3 Receptor in Stimulant and Opiate Use Disorders
The Role of D3 Dopamine-Receptors in Nicotine Dependence: A Synthesis of the Pre-Clinical and Clinical Literature
The Dopamine D3 receptor in Food Addiction
The Dopamine D3 Receptor Pharmacology and the Therapeutic Use of D3 Receptor Ligands in Schizophrenia
D3 receptors and Restless Legs Syndrome
D3 receptors and PET imaging.

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