Drug development in psychiatry / Matthew Macaluso, Sheldon H. Preskorn, Richard C. Shelton, editors.
Macaluso, Matthew, editor.; Preskorn, Sheldon, editor.; Shelton, Richard C., editor.
2023
RM315 .D78 2023
Available Online

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Title
Drug development in psychiatry / Matthew Macaluso, Sheldon H. Preskorn, Richard C. Shelton, editors.
ISBN
9783031210549 electronic book
3031210549 electronic book
3031210530
9783031210532
DOI
https://doi.org/10.1007/978-3-031-21054-9
Published
Cham, Switzerland : Springer, [2023]
Language
English
Description
1 online resource (519 pages) : illustrations (black and white, and colour).
Item Number
10.1007/978-3-031-21054-9 doi
Call Number
RM315 .D78 2023
Dewey Decimal Classification
615.7/88
Summary
This new book reviews clinical trial methodology as it pertains to drug development in psychiatry. The authors will describe the process of drug development in psychiatry from discovery through marketing with the help of clinically relevant examples. The history of drug development in psychiatry is explored dating back to the era of serendipitous discovery and culminating in an era of new and highly focused targets. The book will delineate how drug development in psychiatry has changed and adapted with the discovery of drugs with novel mechanisms of action. Drug Development in Psychiatry elucidates how biomarkers, genetics, and advances in neuroscience and neuroimaging have influenced drug development approaches, which will ultimately change the practice of psychiatry. The book charts the early years of drug discovery by chance observation, reviews the developments of the past 50 years of refined targeting of CNS drugs without the discovery of mechanistically new drugs, and looks to the discovery of mechanistically new drugs, the examination of new targets, genetics, and biomarkers.
Access Note
Access limited to authorized users.
Source of Description
Description based on online resource; title from digital title page (viewed on April 27, 2023).
Added Author
Macaluso, Matthew, editor.
Preskorn, Sheldon, editor.
Shelton, Richard C., editor.
Series
Advances in neurobiology ; 30.
Available in Other Form
DRUG DEVELOPMENT IN PSYCHIATRY.
Linked Resources
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Record Appears in
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All Resources
Drug Development in Psychiatry: The Long and Winding Road from Chance Discovery to Rational Development
The History of Drug Development in Psychiatry: A Lesson in Serendipity
The Evolving Role of Animal Models in the Discovery and Development of Novel Treatments for Psychiatric Disorders
Discovery and Development of Monoamine Transporter Ligands
Drug Development for New Psychiatric Drug Therapies
Post-Approval Research in Drug Development: Priorities and Practices
Discovery of new transmitter systems and hence new drug targets
Reverse engineering drugs
Back to the Future of Neuropsychopharmacology
Targeted Treatments for Fragile X Syndrome
The Difficult Path to the Discovery of Novel Treatments in Psychiatric Disorders Diseases
Biomarkers in Psychiatric Drug Development: From Precision Medicine to Novel Therapeutics
The role of fMRI in drug development: an update
Monoamine Oxidase B (MAO-B): A Target for Rational Drug Development in Schizophrenia Using PET Imaging as an Example
Genomics in Treatment Development
Increased Inflammation and Treatment of Depression: from Resistance to Reuse, Repurposing and Redesign
Experimental medicine approaches in early phase CNS drug development.

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