Hypoxia in cancer : significance and impact on cancer therapy / Sukhes Mukherjee, Jagat Rakesh Kanwar, editors.
Mukherjee, Sukhes, editor.; Kanwar, Jagat Rakesh, editor.
2023
RC103.A4 H97 2023
Available Online

Linked e-resources

Linked Resource Online Access
Concurrent users Unlimited
Authorized users Authorized users
Document Delivery Supplied Can lend chapters, not whole ebooks

Details

Title Hypoxia in cancer : significance and impact on cancer therapy / Sukhes Mukherjee, Jagat Rakesh Kanwar, editors.
ISBN 9789819903139 (electronic bk.)
9819903130 (electronic bk.)
9819903122
9789819903122
DOI https://doi.org/10.1007/978-981-99-0313-9
Published Singapore : Springer, 2023.
Language English
Description 1 online resource (488 pages) : illustrations (black and white, and color).
Item Number 10.1007/978-981-99-0313-9 doi
Call Number RC103.A4 H97 2023
Dewey Decimal Classification 616.9/94
Summary This book reviews the central role of hypoxia in cancer initiation and progression. It discusses the mechanisms of hypoxia in chemoresistance, radioresistance, angiogenesis, vasculogenesis, metastasis, metabolic, and genomic instability. It also explores the potential of hypoxia in the diagnosis and treatment of cancer. The book provides an overview of hypoxia imaging, its biological relevance, and mechanism of action. It helps in understanding the molecular mechanisms of the regulation of senescence by hypoxia. It explores the contribution of hypoxia to immune resistance and immune suppression/tolerance and determines the hypoxia-responsive long non-coding RNAs in regulating hypoxic gene expression at chromatin, transcriptional, and post-transcriptional levels. Further, it presents the functional link between hypoxia and miRNA expressions and hypoxia-regulated miRNAs in cancer cell survival in a low oxygen environment. Lastly, it discusses the applications of tumor-on-a-chip technology for the understanding of hypoxia-tumor microenvironment. This book is a valuable source for oncologists and scientists working to understand the role of hypoxia in cancer and therapeutic approaches.
Access Note Access limited to authorized users.
Source of Description Description based on print version record.
Added Author Mukherjee, Sukhes, editor.
Kanwar, Jagat Rakesh, editor.
Available in Other Form HYPOXIA IN CANCER.
Linked Resources Online Access
Record Appears in Online Resources > Ebooks
All Resources
Chapter 1. Hypoxia and its Biological Implications for Cancer Therapy
Chapter 2. Hypoxia's function in cancer
Chapter 3. Role of Hypoxia and Reactive Oxygen Species in cancer biology
Chapter 4. Hypoxic tumor microenvironment: driver for cancer progression
Chapter 5. Hypoxia and Senescence: Role of Oxygen in Modulation of Tumor Suppression
Chapter 6. Hypoxia Regulated Gene Expression and Metastasis
Chapter 7. piRNA based cancer therapy in hypoxic tumor
Chapter 8. MicroRNA Signatures of Tumor Hypoxia
Chapter 9. Hypoxia and the Metastatic Cascade
Chapter 10. Hypoxia and Extra Cellular Matrix-major drivers of tumor Metastasis
Chapter 11. Role of Hypoxia in Cancer Therapy Introduction
Chapter 12. Hypoxic regulation of telomerase gene expression in cancer
Chapter 13. CRISPR/Cas9-editing-based modeling of tumor hypoxia
Chapter 14. Tumor-on-a-chip: Microfluidic models for Hypoxic tumor microenvironment
Chapter 15. Imaging the Hypoxic Tumor microenvironment in cancer models
Chapter 16. Hypoxia-targeting drugs as new cancer chemotherapy agents Hypoxia-targeting drugs as new cancer chemotherapy agents - Molecular Insights
Chapter 17. Identification of Hypoxia targeting drugs in the tumor microenvironment and prodrug Strategies for Targeting Tumor Hypoxia
Chapter 18. Hypoxia Induced Apoptosis in Cancer Development
Chapter 19. Hypoxia in drug resistance and radioresistance.

Browse Subjects

Show more subjects...

Statistics

from
to
Export