Metabolism of alimentary compounds by the intestinal microbiota and health / François Blachier.
Blachier, François.
2023
QR171.I6
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Title Metabolism of alimentary compounds by the intestinal microbiota and health / François Blachier.
Author Blachier, François.
ISBN 9783031263224 (electronic bk.)
3031263227 (electronic bk.)
3031263219
9783031263217
DOI https://doi.org/10.1007/978-3-031-26322-4
Publication Details Cham : Springer, 2023.
Language English
Description 1 online resource (265 p.)
Item Number 10.1007/978-3-031-26322-4 doi
Call Number QR171.I6
Dewey Decimal Classification 616.3/401
Summary This book provides an overview of the metabolism of dietary compounds by the intestinal microbiota, and on the consequences of such metabolic activity on host metabolism and physiological functions; both in intestinal and peripheral tissues. Over the last years, our understanding of the causal links between microbiota metabolic activity towards dietary and endogenous substrates and human health status has evolved extensively. In this context, the book starts with a comprehensive introduction devoted to the physiological and metabolic functions of the intestinal epithelium, followed by a part dedicated to the way intestine offers board and lodging for microbes being on a short- or long-term stay. The next chapters focus on the utilization of the available substrates from diet by the intestinal bacteria to produce numerous bacterial metabolites, and on the impact of such microbial activity, in the first place for communication between microbes, and for communication between microbes and lodging host. As will be detailed, this latter process of interkingdom communication leads to either beneficial or deleterious effects on intestinal physiology and metabolism. Special attention is given to selected pathophysiological processes namely chronic intestinal inflammation, colorectal carcinogenesis, and diarrhea. Then, the effects of modifications of bacterial metabolites and other bioactive compounds by the host after intestinal absorption, and consequences for peripheral tissue functions are presented. Summarizing the state of the art on what is known about the metabolic crosstalk between gut microbiota and human metabolism, as well as perspectives for further experimental and clinical research, this book provides a useful resource for researchers, professionals, and students with a background in biology, and/or nutrition, medicine, pharmacology, and for those which are involved in the agriculture and food production. By explaining technical terms all along the text, this book should be understandable also for interested non-specialists.
Note 4.3 Dietary Compounds, Bacterial Metabolites, and Diarrhea
Bibliography, etc. Note Includes bibliographical references.
Access Note Access limited to authorized users.
Source of Description Online resource; title from PDF title page (SpringerLink, viewed May 16, 2023).
Available in Other Form Metabolism of Alimentary Compounds by the Intestinal Microbiota and Health
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Intro
Preface
Acknowledgments
Contents
About the Author
1: Physiological and Metabolic Functions of the Intestinal Epithelium: From the Small to the Large Intestine
1.1 The Intestine Displays Multiple Physiological Functions in Addition to Absorption of Components Originating from Food
1.2 The Intestinal Epithelium Represents a Border Between the Outdoor and the Internal Environment
1.3 Structure and Functions of the Small Intestine Epithelium: Metabolism of Nutrients in Epithelial Cells

1.4 Structure and Functions of the Large Intestine Epithelium: Metabolism of Nutrients in the Colonocytes
References
2: Intestine Offers Board and Lodging for Intestinal Microbes on a Short- or Long-Term Stay
2.1 The Human Intestinal Microbiota: A Complex Mixture
2.2 Bacteria Concentration, Composition, and Diversity During the Whole Life
References
3: Metabolism of Dietary Substrates by Intestinal Bacteria and Consequences for the Host Intestine
3.1 Metabolism of Proteins and Amino Acids by the Intestinal Microbiota and Impact on the Intestinal Epithelium Metabolism and...

Amino Acid-Derived Bacterial Metabolites and Effects on the Intestinal Epithelium
Effects of the Amounts of Dietary Proteins on the Intestinal Ecosystem and Consequences
3.2 Metabolism of Polysaccharides by the Intestinal Microbiota and Impact on the Intestinal Epithelium Metabolism and Functions
Polysaccharide-Derived Bacterial Metabolites and Effects on the Intestinal Epithelium
Effects of the Amount of Dietary Polysaccharide on the Intestinal Ecosystem and Consequences
3.3 Metabolism of Lipids by the Intestinal Microbiota

Lipid-Derived Bacterial Metabolites and Effects on the Intestinal Ecosystem
Effects of the Amount of Dietary Lipids on the Intestinal Ecosystem and Consequences
3.4 Metabolism of Purine Nucleotide by the Intestinal Microbiota
3.5 Metabolism of Phytochemicals by the Intestinal Microbiota and Impact on the Intestinal Epithelium Metabolism and Functions
3.6 Osmolality and pH of the Intestinal Luminal Fluid and Effects on the Intestinal Epithelium
3.7 Bacterial Metabolites and the Intestinal Immune System

3.8 Minerals and the Intestinal Microbiota: Consequences for the Intestinal Ecosystem
3.9 Vitamins and the Intestinal Microbiota: Consequences for the Intestinal Ecosystem
3.10 Food Additives and Compounds Produced during Cooking Processes and the Intestinal Microbiota: Consequences for the Intest...
References
4: Alimentation, Bacterial Metabolites, and Host Intestinal Epithelium
4.1 Dietary Compounds, Bacterial Metabolites, and Mucosal Inflammation and Subsequent Healing
4.2 Dietary Compounds, Bacterial Metabolites, and Colorectal Cancer

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