Neurotoxicity of aluminum / edited by Qiao Niu.
Niu, Qiao, editor.
2023
RA1231.A5
Available Online

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Title
Neurotoxicity of aluminum / edited by Qiao Niu.
Edition
Second edition.
ISBN
9789819915927 (electronic bk.)
9819915929 (electronic bk.)
9789819915910
9819915910
DOI
https://doi.org/10.1007/978-981-99-1592-7
Published
Singapore : Springer, 2023.
Language
English
Description
1 online resource (xviii, 313 pages) : illustrations.
Item Number
10.1007/978-981-99-1592-7 doi
Call Number
RA1231.A5
Dewey Decimal Classification
615.9/25673
Summary
This book reviews the scientific literature and the authors own research linking aluminum neurotoxicity with cognitive impairment and Alzheimers disease (AD). It focuses on aluminum levels in the brain, region-specific and subcellular distribution, its relation to neurofibrillary tangles and amyloid betathe pathological features of AD, and the possible mechanism of aluminum inducing these pathological features. Further, the book stresses the importance of aluminums complex speciation chemistry in relation to biology, and details aluminums mechanism in oxidative stress and cell death, especially in connection with apoptosis and necroptosis. The electrophysiological variation and synaptic plasticity induced by aluminum are covered, while the metals debatable role in AD and the cross-talk between aluminum and genetic susceptibility are also discussed, and more recently the relationship between aluminum-induced epigenetic modification on DNA and non-coding RNAs and neuron death and synaptic impairment. The second edition updates eight chapters according to the most recent researches. Content about aluminum-induced AD-like pathological features, neurotoxic effects of aluminum and aluminum alloy nanoparticles(TBD) and alumina nanoparticles induced neurotoxic and neurodevelopmental toxic effects is also added. In closing, this book provides readers with a systematic summary of aluminum neurotoxicity.
Note
Previous edition: 2018.
Bibliography, etc. Note
Includes bibliographical references.
Access Note
Access limited to authorized users.
Source of Description
Description based on print version record.
Added Author
Niu, Qiao, editor.
Series
Advances in experimental medicine and biology.
Available in Other Form
Neurotoxicity of aluminum.
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Chapter 1 Overview of the relationship between aluminum exposure and health of human being.-Chapter 2 The Chemistry of Human Exposure to Aluminum
Chapter 3 Entry and Deposit of Aluminum in Brain
Chapter 4 Aluminum as a CNS and immune system toxin across the life span.-Chapter 5 Occupational exposure to aluminum and cognitive impairment
Chapter 6 Debated relationship between Exposure to Aluminum in Daily Life and Alzheimers Disease
Chapter 7 Animal Model of Aluminum-Induced Alzheimers like Disease
Chapter 8 Aluminum-induced AD-like Pathological Features.-Chapter 9 Aluminum induced neural cells death
Chapter 10 Aluminum-Induced Electrophysiological Variation, Synaptic Plasticity Impairment, and Related Mechanism.-Chapter 11 Cross Talk Between Aluminum and Genetic Susceptibility
Chapter 12 Epigenetic modification in aluminum-induced neuron death and synaptic impairment
Chapter 13 Neurotoxic effects of aluminum and aluminum alloy nanoparticles(TBD)
Chapter 14 Alumina nanoparticles induced neurotoxic and neurodevelopmental toxic effects.

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