Drug discovery and design using natural products / Jorddy Neves Cruz, editor.
Cruz, Jorddy Neves, editor.
2023
RS420
Available Online

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Title Drug discovery and design using natural products / Jorddy Neves Cruz, editor.
ISBN 9783031352058 (electronic bk.)
303135205X (electronic bk.)
9783031352041
3031352041
DOI https://doi.org/10.1007/978-3-031-35205-8
Published Cham, Switzerland : Springer, 2023.
Language English
Description 1 online resource (xi, 542 pages) : illustrations
Item Number 10.1007/978-3-031-35205-8 doi
Call Number RS420
Dewey Decimal Classification 615.1/9
Summary Historically, natural products have great relevance for the development of new drugs. Natural molecules, in addition to directly providing new compounds with different therapeutic functions have provided scaffolds and a great diversity of structures that serve as inspiration for the design and discovery of new drugs. The great structural complexity and the significant number of natural compounds that can be obtained and their advantages also present some historical problems that need to be overcome. Issues such as difficulty in isolation, difficulty in synthesizing compounds found in nature in the laboratory, screening to evaluate the biological properties of these compounds, and structural optimization to enhance the pharmacological properties of biomolecules; are some of the main difficulties encountered in research with natural products and in the design/discovery of new medicines. Therefore, this book addresses the great scientific advances that provide practical solutions to using natural products to develop new drugs. We address topics related to the genesis of research projects that use natural products to design new drugs. We address the discovery of new species, initial processes for identification and extraction of compounds, isolation and identification of these structures, techniques, and advances in vitro and in vivo methods that support the discovery of new natural drugs, synthesis of new compounds from natural molecules, in silico optimization processes of potentially promising compounds.
Note Includes index,
Access Note Access limited to authorized users.
Source of Description Online resource; title from PDF title page (SpringerLink, viewed September 5, 2023).
Added Author Cruz, Jorddy Neves, editor.
Available in Other Form Aspiration Based Decision Support Systems
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Part I. Genesis of research projects that use natural products to design new drugs - - Part II. Initial processes for identifying and extracting compounds: isolation and identifying these structures
Part III. Screening of compounds using molecular modeling approaches: optimization of natural compounds using In silico methods
Part IV. Synthesis and encapsulation of compounds of natural origin
Part V. Identification of molecular targets of natural molecules and biological potential.

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