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Historic outline of the development of drugs targeting B-cells
Understanding B-cell biology
Pharmacological effects and mechanisms of action of agents blocking B cells
Systemic lupus erythematosus: direct B-cell blocking
Systemic lupus erythematosus: indirect B-cell blocking
B-cell targeted therapies in rheumatoid arthritis
B-cell targeted therapies in Primary Sj?gren Syndrome
Targeting B cells in ANCA-associated vasculitis
B-cell targeted therapies in systemic sclerosis and inflammatory myopathies
B-cell targeted therapies in cryoglobulinemia
B-cell targeted therapies in autoimmune cytopenias and thrombosis
Targeting B cells in neurological autoimmune diseases
Targeting B cells in other systemic autoimmune diseases
Safety of B-cell targeted therapies
The future potential of biosimilars targeting B-cells.

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