Breast cancer biology for the radiation oncologist [electronic resource] / Jonathan Strauss, William Small, Gayle E. Woloschak, editors.
Strauss, Jonathan, editor.; Small, William, Jr., editor.; Woloschak, Gayle E., editor.
2015
RC280.B8
Available Online

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Title Breast cancer biology for the radiation oncologist [electronic resource] / Jonathan Strauss, William Small, Gayle E. Woloschak, editors.
ISBN 9783642312205 electronic book
3642312209 electronic book
9783642312199
DOI https://doi.org/10.1007/978-3-642-31220-5
Published Heidelberg : Springer, [2015]
Language English
Description 1 online resource.
Other Standard Identifiers 10.1007/978-3-642-31220-5 doi
Call Number RC280.B8
Dewey Decimal Classification 616.99449
Summary Breast Cancer Biology for the Radiation Oncologist is the first textbook of its kind devoted to describing the biological complexities of breast cancer in a way that is relevant to the radiation oncologist. Radiation Oncology has long treated breast cancer as a single biological entity, with all treatment decisions being based on clinical and pathologic risk factors. We are now beginning to understand that biological subtypes of breast cancer may have different risks of recurrence as well as different intrinsic sensitivity to radiotherapy. Multi-gene arrays that have for years been used to predict the risk of distant recurrence and the value of systemic chemotherapy may also have utility in predicting the risk of local recurrence. Additionally, the targeted agents used to treat breast cancer may interact with radiotherapy in ways that can be beneficial or undesirable. All of these emerging issues of central importance to radiation oncologists are extensively discussed in this book, and practical treatment recommendations based on available clinical evidence are presented whenever possible.
Bibliography, etc. Note Includes bibliographical references.
Access Note Access limited to authorized users.
Added Author Strauss, Jonathan, editor.
Small, William, Jr., editor.
Woloschak, Gayle E., editor.
Series Medical Radiology.
Available in Other Form Print version: 9783642312199
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Biological subtypes of breast cancer
Oncogene amplification and Herceptin
Current clinical use of genetic profiling
Biology of DCIS and progression to invasive disease
Cancer Stem Cells and Radiotherapy
Genetic basis of normal tissue radiosensitivity and late toxicity
Genetic syndromes and radiotherapy in breast cancer
Experimental therapies in breast cancer.

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