The cytoskeleton in health and disease [electronic resource] / Heide Schatten, editor.
Schatten, Heide, editor.
2015
QH603.C96
Available Online

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Title The cytoskeleton in health and disease [electronic resource] / Heide Schatten, editor.
ISBN 9781493929047 electronic book
1493929046 electronic book
9781493929030
DOI https://doi.org/10.1007/978-1-4939-2904-7
Published New York, NY : Springer, 2015.
Language English
Description 1 online resource (xii, 395 pages) : color illustrations
Item Number 10.1007/978-1-4939-2904-7 doi
Call Number QH603.C96
Dewey Decimal Classification 571.6/54
Summary This volume℗ℓexplores the cytoskeleton, examining its structural and functional roles and its dysfunctions which often lead to disease.℗ℓMicrotubules, microfilaments, intermediate filaments, and cytoskeletal functions and dysfunctions in different organ systems are thoroughly discussed. The text is organized into four sections, each of which covers℗ℓspecific subtopics. These consist of℗ℓan introductory chapter℗ℓfollowed by topics of current interest and expert-provided contributions which℗ℓinclude each topic's℗ℓkey cell and molecular details. Comprehensive℗ℓyet concise,℗ℓ℗ℓThe Cytoskeleton in Health and Disease℗ℓpresents cutting- edge new℗ℓknowledge℗ℓbalanced with background information, both of which are readily understandable for the newcomer and for the experienced researcher alike. The book℗ℓhighlights the new aspects of the℗ℓresearch and its impact on℗ℓ the design of℗ℓnew strategies or the identification of new targets for therapeutic intervention. This book will be essential reading for scientists, students, teachers who are interested in expanding their knowledge related to the cytoskeleton for diagnostic, therapeutic or℗ℓresearch-based purposes.
Note Includes index.
Access Note Access limited to authorized users.
Source of Description Online resource; title from PDF title page (viewed August 26, 2015)
Added Author Schatten, Heide, editor.
Available in Other Form Print version: 9781493929030
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Part 1. Overview of the Cytoskeleton
Brief Overview of the Cytoskeleton
Part 2. Focus on Cytoskeletal Interactions
Cytoskeleton Dynamics in Health and Disease: Role of Molecular Switches and Rheostats
Regulation of Cytoskeleton by the Rho Family of GTPases in Hematopoietic Stem Cells in Health and Disease
The Role of the Cytoskeleton in Cell Migration, Its Influence on Stem Cells and the Special Role of GFAP in Glial Functions
Centrosome-Microtubule Interactions in Health, Disease, and Disorders
Cytoskeletal Elements and Reproductive Success in Animals
Part 3. Focus on Microtubules
Cytoskeleton and Regulation of Mitochondrial Translocation in Mammalian Eggs
Tubulin Detyrosination in Epithelial Cells
Mutations in Adenomatous Polyposis Coli, Their Role in Cytoskeletal Dynamics and Cancer Onset
Small GTPases Act as Cellular Switches in the Context of Cilia
Part 4. Focus on Intermediate Filaments
Desmin Plays Dual Structural and Regulatory Functions Through Its Interaction with Partners in Muscle
Desmin Filaments and Desmin-Related Myopathy
Possible Functions of Intermediate Filaments in Mammalian Ovarian Follicles and Oocytes
Part 5. Focus on Microfilaments
Actin Organizing Proteins in Regulation of Osteoclast Function
The Role of Drebrin-Binding Stable Actin Filaments in Dendritic Spine Morphogenesis
The Role of the Actin Cytoskeleton in Cancer and Its Potential Use as a Therapeutic Target.

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