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About the Editor; Contents; Contributors; Part I: Background Topics; 1: Introduction; Part II: Oral Infections and General Health; 2: Dental Caries and General Health in Children and Adults; 2.1 Introduction; 2.2 Link between Caries and General Diseases; 2.3 Common Research Designs; 2.4 Obesity/Overweight; 2.5 Asthma; 2.6 Diabetes; 2.7 Congenital Heart Disease; 2.8 Cancers; 2.9 Cleft Lip Palate; 2.10 Neuropsychiatric Disorders; 2.11 Aging and Cognitive Impairment; 2.12 Caries Management; Conclusions; References.
3: Plausible Mechanisms Explaining the Association of Periodontitis with Cardiovascular Diseases3.1 Introduction; 3.2 Definitions of the Conditions; 3.2.1 Periodontitis; 3.2.2 Atherosclerosis and Acute Atherosclerotic Events; 3.3 Bacteremia and Consequences for the Cardiovascular System; 3.4 Immunologic Reactions; 3.5 Pro-inflammatory State; 3.6 Prothrombotic State; 3.7 Dyslipidemia; 3.8 A Common Genetic Background; 3.9 Perspective and Concluding Remarks; References; 4: Linkage Between Periodontal Disease and Diabetes Mellitus; 4.1 Diabetes Mellitus.
4.2 Association of Periodontitis and DM4.2.1 Population Data; 4.2.2 Biological Similarities; 4.2.3 Possible Mechanisms of Association; 4.2.4 Outcome of Periodontal Treatment; Conclusion; References; 5: Linkage Between Periodontal Disease and Rheumatoid Arthritis; 5.1 Rheumatoid Arthritis; 5.2 Association of Periodontitis and RA; 5.2.1 Population Data; 5.2.2 Biological Similarities; 5.2.3 Possible Mechanisms of Association; 5.2.4 Outcome of Periodontal Treatment; Conclusion; References; 6: Association Between Dental Infections and Renal and Liver Diseases; 6.1 Introduction.
6.2 Renal Diseases6.3 Streptococcal Glomerulonephritis; 6.4 Liver Diseases; Conclusion; References; 7: Association Between Oral Infections and Cancer Risk; 7.1 Introduction; 7.2 Oral and Dental Infections and Cancer Epidemiology; 7.3 Infection-Driven Mechanisms in Carcinogenesis; 7.4 Acetaldehyde Production by Oral Microorganisms; 7.5 Caries, Periodontitis, and Cancer; 7.6 Role of Saliva in the Oral Infection-Linked Carcinogenesis; Conclusion; References; 8: Oral Candidiasis and the Medically Compromised Patient; 8.1 Introduction; 8.2 Clinicopathological Aspects.
8.2.1 Histopathology8.2.2 Immunological Aspects; 8.3 Oral Candidiasis in the Medically Compromised Patient; 8.3.1 Oral Candidiasis as Adverse Drug Reaction; 8.3.2 Diabetes Mellitus and Oral Candidiasis; 8.3.3 HIV Infection and Oral Candidiasis; 8.3.4 Recipients of Organ and Haematopoietic Cell Transplants and Cancer Therapy; 8.4 Chronic Mucocutaneous Candidiasis; 8.5 Diagnostic Methods; 8.5.1 Culture of Clinical Samples in Order to Quantify and Identify the Candida Load; 8.5.2 Smears; 8.5.3 Biopsy; 8.5.4 Molecular Techniques for Candida Identification; References.
3: Plausible Mechanisms Explaining the Association of Periodontitis with Cardiovascular Diseases3.1 Introduction; 3.2 Definitions of the Conditions; 3.2.1 Periodontitis; 3.2.2 Atherosclerosis and Acute Atherosclerotic Events; 3.3 Bacteremia and Consequences for the Cardiovascular System; 3.4 Immunologic Reactions; 3.5 Pro-inflammatory State; 3.6 Prothrombotic State; 3.7 Dyslipidemia; 3.8 A Common Genetic Background; 3.9 Perspective and Concluding Remarks; References; 4: Linkage Between Periodontal Disease and Diabetes Mellitus; 4.1 Diabetes Mellitus.
4.2 Association of Periodontitis and DM4.2.1 Population Data; 4.2.2 Biological Similarities; 4.2.3 Possible Mechanisms of Association; 4.2.4 Outcome of Periodontal Treatment; Conclusion; References; 5: Linkage Between Periodontal Disease and Rheumatoid Arthritis; 5.1 Rheumatoid Arthritis; 5.2 Association of Periodontitis and RA; 5.2.1 Population Data; 5.2.2 Biological Similarities; 5.2.3 Possible Mechanisms of Association; 5.2.4 Outcome of Periodontal Treatment; Conclusion; References; 6: Association Between Dental Infections and Renal and Liver Diseases; 6.1 Introduction.
6.2 Renal Diseases6.3 Streptococcal Glomerulonephritis; 6.4 Liver Diseases; Conclusion; References; 7: Association Between Oral Infections and Cancer Risk; 7.1 Introduction; 7.2 Oral and Dental Infections and Cancer Epidemiology; 7.3 Infection-Driven Mechanisms in Carcinogenesis; 7.4 Acetaldehyde Production by Oral Microorganisms; 7.5 Caries, Periodontitis, and Cancer; 7.6 Role of Saliva in the Oral Infection-Linked Carcinogenesis; Conclusion; References; 8: Oral Candidiasis and the Medically Compromised Patient; 8.1 Introduction; 8.2 Clinicopathological Aspects.
8.2.1 Histopathology8.2.2 Immunological Aspects; 8.3 Oral Candidiasis in the Medically Compromised Patient; 8.3.1 Oral Candidiasis as Adverse Drug Reaction; 8.3.2 Diabetes Mellitus and Oral Candidiasis; 8.3.3 HIV Infection and Oral Candidiasis; 8.3.4 Recipients of Organ and Haematopoietic Cell Transplants and Cancer Therapy; 8.4 Chronic Mucocutaneous Candidiasis; 8.5 Diagnostic Methods; 8.5.1 Culture of Clinical Samples in Order to Quantify and Identify the Candida Load; 8.5.2 Smears; 8.5.3 Biopsy; 8.5.4 Molecular Techniques for Candida Identification; References.