Helicobacter pylori research [electronic resource] : from bench to bedside / Steffen Backert, Yoshio Yamaoka, editors.
Backert, Steffen, editor.; Yamaoka, Yoshio, editor.
2016
QR82.Z9
Available Online

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Title Helicobacter pylori research [electronic resource] : from bench to bedside / Steffen Backert, Yoshio Yamaoka, editors.
ISBN 9784431559368 (electronic book)
4431559361 (electronic book)
9784431559344
Published Japan : Springer, [2016]
Language English
Description 1 online resource (xi, 613 pages) : color illustrations, maps
Call Number QR82.Z9
Dewey Decimal Classification 579.3/23
Summary This book provides the current updated knowledge on all essential aspects in the rapidly evolving area of Helicobacter pylori research. H. pylori is a class I carcinogen and one of the most common infections in the world. While most people colonized by H. pylori will remain asymptomatic, up to 20 % of them may develop serious gastroduodenal disease such as peptic ulcers or gastric cancer. H. pylori is the only known bacterium linked to the development of cancer and consequently is an important focus of research. Outstanding international experts from diverse scientific disciplines contribute here to give detailed insights into the current understanding concerning the physiology and role of this pathogen. Both basic science and clinical research with actual practical consequences are taken into account. The chapters target microbiology, epidemiology, genetics, biochemistry, interactions with the immune system, signal transduction, pathogenic mechanisms in the gastroduodenal mucosa, gastric disease development, and therapy including antibiotics or probiotics treatment as well as vaccination strategies. This book is an important reference not only for clinicians but also microbiologists. It provides in a single volume an up-to-date summary of our current knowledge of this microbe and the multiple ways in which it impacts upon public health in all parts of the world.
Bibliography, etc. Note Includes bibliographical references and index.
Access Note Access limited to authorized users.
Source of Description Online resource; title from PDF title page (viewed May 16, 2016).
Added Author Backert, Steffen, editor.
Yamaoka, Yoshio, editor.
Available in Other Form Helicobacter pylori research : from bench to bedside.
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PART 1 BACTERIOLOGY AND MOLECULAR BIOLOGY
1 Helicobacter pylori: genetics, recombination, population structure and human migrations
2 Adaptation of Helicobacter pylori metabolism to persistent gastric colonization
3 Virulence mechanisms of Helicobacter pylori: an overview
4 Roles of the cagPAI and CagA on gastroduodenal diseases
5 Helicobacter pylori vacuolating toxin
6 Roles of the BabA and the SabA adhesins in gastroduodenal diseases
7 Emerging novel virulence factors of Helicobacter pylori
8 The primary transcriptome and non-coding RNA repertoire of Helicobacter pylori
9 Genome evolution: Helicobacter pylori as an extreme model
10 Non-Helicobacter pylori Helicobacter infections in humans and animals
PART 2 IMMUNE RESPONSES AND HOST FACTORS
11 Animal Models of Helicobacter pylori Infection
12 Helicobacter pylori and the host immune response
13 The role of inflammatory responses in mouse gastric tumorigenesis
14 Influence of host gene polymorphisms on development of gastroduodenal diseases
PART 3 HELICOBACTER PYLORI-ASSOCIATED DISEASES
15 Helicobacter pylori and Nonmalignant Diseases
16 Helicobacter pylori and gastrointestinal polyps
17 Helicobacter pylori infection and gastric cancer
18 Helicobacter pylori infection and MALT lymphoma
19 Helicobacter pylori infection in children
PART 4 TREATMENT OF HELICOBACTER PYLORI
20 Helicobacter pylori therapy
21 Management of H. pylori infection in Europe
22 Population-based strategies for Helicobacter pylori-associated disease management: Latin American perspective
23 Population-based strategies for Helicobacter pylori-associated disease management: Asian perspective
24 Probiotics as an alternative therapy for Helicobacter pylori-associated diseases
25 Vaccination against Helicobacter pylori infection.

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