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Foreword; Preface; Contents; List of Figures; List of Tables; Introduction; References; Chapter 1: Current Problems of Complex Disease Genes Mapping; 1.1 General Problems of Complex Disease Genes Mapping; 1.2 Current Approaches of Schizophrenia Spectrum Disease Gene Mapping; 1.3 The Current State of Gene Mapping of Schizophrenia Spectrum Disorders; References; Chapter 2: Descriptions and Methods of Study in Selected Genetic Isolates of Dagestan; 2.1 History and Ethno-linguistic Diversity of Dagestan; 2.2 Genetic and Demographic Structure of the Selected Isolates
2.3 Methods of Clinical Studies2.4 Molecular-Genetic Methods of Study; 2.5 Genetic and Statistical Methods of Experimental Data Analysis; References; Chapter 3: Selection of Populations for Mapping Genes of Complex Diseases; 3.1 Principles of Selection of Populations for Complex Disease Gene Mapping; 3.2 Ethnogenomic Structure of Dagestan Populations; 3.3 Genetic Epidemiology Study of Selected Genetic Isolates with the Aggregation of Schizophrenia Spectrum Disorders; 3.4 Gene Pool of Selected Isolates for Mapping Genes of Schizophrenia
3.5 Role of Inbreeding in the Aggregation of a Schizophrenia and in Its Age of OnsetReferences; Chapter 4: Mapping Genes of Schizophrenia in Selected Dagestan Isolates; 4.1 Haplotype Analysis in Pedigrees Ascertained in the Isolates; 4.2 Genome-Wide Nonparametric Linkage Analysis of Schizophrenia in Selected Isolates; 4.3 Genome-Wide Parametric Linkage Analysis of Schizophrenia in Selected Isolates; 4.4 Cross-Population Analysis of Genome-Wide Linkages Scan for Schizophrenia in Selected Isolates; References; Chapter 5: Common Structural Genomic Variants in Linked with SCZ Regions
5.1 Copy Number Variations and Runs of Homozygosity Analyses in Linked with SCZ Genomic Regions in Pedigrees of Selected Isola...5.2 Effect of Inbreeding on CNV and ROH Segments Sizes (Kb) and on Marker Numbers; 5.3 Cross-Isolate Study of Structural Genomic Variations in Linked with Schizophrenia Regions; References; Conclusions; Appendix: List of Genome-Wide Scanned Loci and Markers in Studied Dagestan Genetic Isolates (Weber/CHLC 9.0 Markers)
2.3 Methods of Clinical Studies2.4 Molecular-Genetic Methods of Study; 2.5 Genetic and Statistical Methods of Experimental Data Analysis; References; Chapter 3: Selection of Populations for Mapping Genes of Complex Diseases; 3.1 Principles of Selection of Populations for Complex Disease Gene Mapping; 3.2 Ethnogenomic Structure of Dagestan Populations; 3.3 Genetic Epidemiology Study of Selected Genetic Isolates with the Aggregation of Schizophrenia Spectrum Disorders; 3.4 Gene Pool of Selected Isolates for Mapping Genes of Schizophrenia
3.5 Role of Inbreeding in the Aggregation of a Schizophrenia and in Its Age of OnsetReferences; Chapter 4: Mapping Genes of Schizophrenia in Selected Dagestan Isolates; 4.1 Haplotype Analysis in Pedigrees Ascertained in the Isolates; 4.2 Genome-Wide Nonparametric Linkage Analysis of Schizophrenia in Selected Isolates; 4.3 Genome-Wide Parametric Linkage Analysis of Schizophrenia in Selected Isolates; 4.4 Cross-Population Analysis of Genome-Wide Linkages Scan for Schizophrenia in Selected Isolates; References; Chapter 5: Common Structural Genomic Variants in Linked with SCZ Regions
5.1 Copy Number Variations and Runs of Homozygosity Analyses in Linked with SCZ Genomic Regions in Pedigrees of Selected Isola...5.2 Effect of Inbreeding on CNV and ROH Segments Sizes (Kb) and on Marker Numbers; 5.3 Cross-Isolate Study of Structural Genomic Variations in Linked with Schizophrenia Regions; References; Conclusions; Appendix: List of Genome-Wide Scanned Loci and Markers in Studied Dagestan Genetic Isolates (Weber/CHLC 9.0 Markers)