Asthma : targeted biological therapies / Girolamo Pelaia, Alessandro Vatrella, Rosario Maselli.
Pelaia, Girolamo, author.; Vatrella, Alessandro, author.; Maselli, Rosario, author.
2017
RC591
Available Online

Linked e-resources

Linked Resource Online Access
Concurrent users Unlimited
Authorized users Authorized users
Document Delivery Supplied Can lend chapters, not whole ebooks

Details

Title Asthma : targeted biological therapies / Girolamo Pelaia, Alessandro Vatrella, Rosario Maselli.
Author Pelaia, Girolamo, author.
ISBN 9783319460079 (electronic book)
3319460072 (electronic book)
9783319460055
3319460056
DOI https://doi.org/10.1007/978-3-319-46007-9
Published Cham, Switzerland : Springer, 2017.
Language English
Description 1 online resource
Other Standard Identifiers 10.1007/978-3-319-46007-9 doi
Call Number RC591
Dewey Decimal Classification 616.2/3806
Summary This book focuses on the fundamentals of the use of biologics in asthma, describing the rationale, principles, mechanisms of action, and indications. It offers an excellent balance between basic science and the analysis of clinical trials, updating readers with new developments that are changing the global scenario for targeted biological anti-asthma therapies, especially with regard to more severe disease. A range of therapies are considered, from the humanized monoclonal anti-IgE antibody omalizumab, widely approved as add-on treatment for inadequately controlled disease, through to emerging biologics for which evidence supportive of efficacy is accumulating, including anti-IL-5, anti-IL-4, and anti-IL-13 therapies. One aspect to emerge is the variability in individual response, which suggests a need for characterization of different asthma subtypes to permit the effective implementation of phenotype-targeted treatments. This book will be of interest for pulmonologists, clinical immunologists, and physicians seeking sound information on these therapies, but also for scientists and pharmacologists wishing to enhance their knowledge of the therapeutic implications of the cellular and molecular mechanisms that underlie severe, uncontrolled asthma.
Bibliography, etc. Note Includes bibliographical references.
Access Note Access limited to authorized users.
Digital File Characteristics text file PDF
Source of Description Online resource; title from PDF title page (viewed December 15, 2016)
Added Author Vatrella, Alessandro, author.
Maselli, Rosario, author.
Available in Other Form Print version: 9783319460055
Linked Resources Online Access
Record Appears in Online Resources > Ebooks
All Resources
Introduction
Inflammatory cellular patterns in asthma
Airway remodelling in asthma
Anti-IgE antibodies
IL-5-targeted antibodies
IL-4-specific biologics
Anti-IL-13 therapies
Anti-TNFalpha-antibodies
Biologic treatments targeted to innate cytokines
Other biologic drugs
Conclusions and future perspectives.

Browse Subjects

Show more subjects...

Statistics

from
to
Export