The immune response to implanted materials and devices : the impact of the immune system on the success of an implant / Bruna Corradetti, editor.
Corradetti, Bruna, editor.
2017
R857.M3
Available Online

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Title
The immune response to implanted materials and devices : the impact of the immune system on the success of an implant / Bruna Corradetti, editor.
ISBN
9783319454337 (electronic book)
3319454331 (electronic book)
9783319454313
3319454315
DOI
https://doi.org/10.1007/978-3-319-45433-7
Published
Cham, Switzerland : Springer, 2017.
Copyright
©2017
Language
English
Description
1 online resource (254 pages) : illustrations.
Item Number
10.1007/978-3-319-45433-7 doi
Call Number
R857.M3
Dewey Decimal Classification
610.28
Summary
This book provides a comprehensive overview of the cascade of events activated in the body following the implant of biomaterials and devices. It is one of the first books to shed light on the role of the host immune response on therapeutic efficacy of an implant, and reviews the state-of-the-art for both basic science and medical applications. The text examines advantages and disadvantages of the use of synthetic versus natural biomaterials. Particular emphasis is placed on the role of biomimicry in the development of smart strategies able to modulate infiltrating immune cells, thus reducing side effects (such as acute and chronic inflammation, fibrosis and/or implant rejection) and improving the therapeutic outcome (healing, tissue restoration). Current cutting-edge approaches in tissue engineering, regenerative medicine, and nanomedicine offer the latest insights into the role immunomodulation plays in improving tolerance during cells and tissue transplant, in the treatment of orthopaedic, pancreatic, and hepatic diseases.The Immune Response to Implanted Materials and Devices is intended for an audience of graduate students and professional researchers in both academia and industry interested in the development of smart strategies, which are able to exploit the self-healing properties of the body and achieve functional tissue restoration.
Note
Includes index.
Access Note
Access limited to authorized users.
Digital File Characteristics
text file PDF
Added Author
Corradetti, Bruna, editor.
Available in Other Form
Print version: 9783319454313
Linked Resources
Online Access
Record Appears in
Online Resources > Ebooks
All Resources
Host response to implanted materials and devices
overview
Innate and acquired immunity: umoral and cellular components (Protein adsorption, cell recruitment, tissue response)
Acute/Chronic inflammation, foreign body reaction
implications
Macrophages: from immune response to tissue restoration
Host response to cell-grafted biomaterials
Host response to therapeutic nanoparticles
Host response to synthetic versus natural biomaterials (The effects of the composition, structure on function, stability, and final outcome)
Biomimicry at the cell-material interface to mitigate the immune reaction
Bioactive materials design for immunomodulation
exploiting the patient's own body machinery to achieve functional tissue restoration
Host response to materials for orthopaedic applications: current approaches and future perspectives
Methods to activate cellular immunity or determine immune evasion.

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