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Can lend chapters, not whole ebooks
Title
Immunotherapy for gastrointestinal cancer / David Kerr, Rebecca Johnson, editors.
ISBN
9783319430638 (electronic book)
3319430637 (electronic book)
9783319430614
Published
Cham, Switzerland : Springer, 2017.
Language
English
Description
1 online resource.
Other Standard Identifiers
10.1007/978-3-319-43063-8 doi
Call Number
RC280.D5
Dewey Decimal Classification
616.99/4333
Summary
This book is about the manipulation of the immune system as a therapeutic approach to gastrointestinal cancer and its clinical applications, exploring therapeutic approaches which might be taken under the broad banner of immunotherapy. Starting by introducing concepts of modern immunology, the clinical applications of immunotherapy are then discussed. The reader will learn about the three broad classes of immune therapeutic agents: cell-based treatment; antibody therapy; cytokine application and the key effector cells and mechanisms which might cause tumour rejection. The reverse side of this equation, the genetic and molecular mechanisms which the tumour can use to escape immune control and regulation, is also discussed. Through reviewing the most up-to-date evidence, this volume provides an overview of the important scientific lessons learned from past failure of immunotherapeutics in the clinic and highlights more positive recent data, coupled to practical guidelines for clinical usage. Written by a team of worldwide experts, this is an indispensable guide for medical oncologists, surgical oncologists, radiation therapists, pharmacists, oncology nurse specialists. .
Note
Includes index.
Access Note
Access limited to authorized users.
Digital File Characteristics
text file PDF
Source of Description
Online resource; title from PDF title page (SpringerLink, viewed January 18, 2017).
Available in Other Form
Print version: 9783319430614
Introduction to modern immunology
Cell based therapy ? modified cancer cells
Vaccines for GI cancer
Antibody delivery of radioactive ?warheads? and cytotoxins
Antibodies which inhibit specific cell pathways
PD1 and PD1l immune checkpoint inhibitors
The Role of the JAK/STAT Signaling Pathway in Immunoregulation of Gastrointestinal Cancers
Hyper mutated colorectal cancer and neoantigen load
Antibodies which inhibit specific cell pathways, colorectal cancer.
