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Table of Contents
1 Biochemistry and mechanism of action of collagen
2 Pre-Clinical evaluation and early clinical trials in USA
3 Dupuytren's Disease: topographic anatomy of lesions
4 Experimental phase in Europe: protocol and first results
5 Preparation, injection and traction procedures (Pearls and Tips & Tricks): technical evolution
6 First web space, thumb, and nodules
7 Rehabilitation after treatment
8 Collagenase today: follow-up studies, recurrence, dosage, drug safety
9 American and European Regulations
10 Collagenase: future perspectives. .
2 Pre-Clinical evaluation and early clinical trials in USA
3 Dupuytren's Disease: topographic anatomy of lesions
4 Experimental phase in Europe: protocol and first results
5 Preparation, injection and traction procedures (Pearls and Tips & Tricks): technical evolution
6 First web space, thumb, and nodules
7 Rehabilitation after treatment
8 Collagenase today: follow-up studies, recurrence, dosage, drug safety
9 American and European Regulations
10 Collagenase: future perspectives. .