Stem cell genetics for biomedical research : past, present, and future / Raul Delgado-Morales, editor.
2018
QH588.S83 S74 2018
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Details
Title
Stem cell genetics for biomedical research : past, present, and future / Raul Delgado-Morales, editor.
ISBN
9783319906959 (electronic book)
331990695X (electronic book)
3319906941
9783319906942
331990695X (electronic book)
3319906941
9783319906942
Published
Cham, Switzerland : Springer, [2018]
Language
English
Description
1 online resource (xi, 426 pages)
Item Number
10.1007/978-3-319-90695-9 doi
Call Number
QH588.S83 S74 2018
Dewey Decimal Classification
616.02/774
Summary
This book looks at where stem cell technology is presently and how it is instrumental in advancing the field of disease modeling and cell transplantation. By focusing on major human disorders such as Alzheimer's disease, cancer, and heart disorders, the book summarizes the major findings in the field of human stem cells and dissect the current limitations on our understanding of stem cells biology. The chapters focus on the genetics, genomics, epigenetics and physiology of stem cells models, together with technological advances on molecular biology such as CRISPR/Cas9 or epigenetic editing, that will be instrumental in the future of human disease modeling and treatment. In base of the limitations of current disease models and in front of the unmet necessity of finding therapeutical interventions for human disorders, the availability of stem cell technology has opened new doors for several fields. The unlimited self-renewal capacity and more extensive differentiation potential of stem cells offers a theoretically inexhaustible and replenishable source of any cell subtype. Since Professor Shinya Yamanaka described it, 10 years ago in his seminal paper, that somatic cells could be reprogrammed to inducible stem cells (iPSC) just by expressing four transcription factors, the field of has exploded, especially its applications in biomedical research.
Bibliography, etc. Note
Includes bibliographical references and index.
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Access limited to authorized users.
Digital File Characteristics
text file PDF
Source of Description
Online resource; title from digital title page (viewed on July 27, 2018).
Added Author
Delgado-Morales, Raul, editor.
Available in Other Form
Print version: 9783319906942
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