Molecular mechanisms of inflammation : induction, resolution and escape by Helicobacter pylori / Steffen Backert, editor.
Backert, Steffen.
2019
QR201.H44
Available Online

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Title Molecular mechanisms of inflammation : induction, resolution and escape by Helicobacter pylori / Steffen Backert, editor.
ISBN 9783030151386 (electronic book)
3030151387 (electronic book)
9783030151409
DOI https://doi.org/10.1007/978-3-030-15
Imprint Cham : Springer, 2019.
Language English
Description 1 online resource (378 pages).
Other Standard Identifiers 10.1007/978-3-030-15
Call Number QR201.H44
Dewey Decimal Classification 616.9/041
Summary This book focuses on immune reactions and interactions of humans with Helicobacter pylori - a human pathogen connected to gastritis, peptic ulcers and even gastric cancer. With nearly half of the worlds population colonized, it has been characterized as one of the most successful pathogens for more than 100,000 years of co-evolution with its host. The respective chapters discuss not only how H. pylori infection is considered a paradigm for persistent bacterial infection and chronic inflammation, but also how the infection might be connected to host protection against gastro-esophageal diseases, asthma, and other allergic disease manifestations. Readers will gain essential insights into the roles of specific factors in the immune response and learn about the impact of genetic polymorphisms on the risk of gastric carcinogenesis. In addition, the book discusses the strategies used by this bacterium, which allow it to colonize specific sites in the stomach, interact with the microbiome, evade immune surveillance and undermine the resolution of inflammation during persistent infection. This volume presents a concise summary of recent advances in the areas of induction, resolution and escape of inflammation, innate and adaptive immunity, gastric disease development, as well as treatment and vaccination against H. pylori. Accordingly, it offers a valuable asset for scientists and clinicians alike.
Access Note Access limited to authorized users.
Source of Description Description based on print version record.
Added Author Backert, Steffen.
Series Current topics in microbiology and immunology ; v. 421.
Available in Other Form Molecular Mechanisms of Inflammation: Induction, Resolution and Escape by Helicobacter Pylori
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Record Appears in Online Resources > Ebooks
All Resources
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Importance of toll-like receptors in pro-inflammatory and anti-inflammatory responses by Helicobacter pylori infection
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Carbohydrate-dependent and antimicrobial peptide defense mechanisms against Helicobacter pylori infections
The sweeping role of cholesterol depletion in the persistence of Helicobacter pylori infections
Helicobacter pylori deregulates T and B cell signaling to trigger immune evasion
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Impact of the gastrointestinal microbiome in health and disease: co-evolution with the host immune system
Resolution of gastric cancer-promoting inflammation: a novel strategy for anti-cancer therapy.

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