Targeted Therapies for Lung Cancer / Ravi Salgia, editor.
2019
RC280.L8
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Details
Title
Targeted Therapies for Lung Cancer / Ravi Salgia, editor.
ISBN
9783030178321 (electronic book)
3030178323 (electronic book)
9783030178314
3030178315
3030178323 (electronic book)
9783030178314
3030178315
Publication Details
Cham : Springer, 2019.
Language
English
Description
1 online resource (244 pages)
Item Number
10.1007/978-3-030-17
Call Number
RC280.L8
Dewey Decimal Classification
616.99/42406
Summary
This book contextualizes translational research and provides an up to date progress report on therapies that are currently being targeted in lung cancer. It is now well established that there is tremendous heterogeneity among cancer cells both at the inter- and intra-tumoral level. Further, a growing body of work highlights the importance of targeted therapies and personalized medicine in treating cancer patients. In contrast to conventional therapies that are typically administered to the average patient regardless of the patients genotype, targeted therapies are tailored to patients with specific traits. Nonetheless, such genetic changes can be disease-specific and/or target specific; thus, the book addresses these issues manifested in the somatically acquired genetic changes of the targeted gene. Each chapter is written by a leading medical oncologist who specializes in thoracic oncology and is devoted to a particular target in a specific indication. Contributors provide an in-depth review of the literature covering the mechanisms underlying signaling, potential cross talk between the target and downstream signaling, and potential emergence of drug resistance.
Access Note
Access limited to authorized users.
Source of Description
Description based on print version record.
Added Author
Salgia, Ravi.
Series
Current cancer research.
Available in Other Form
Targeted Therapies for Lung Cancer.
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Online Access
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Table of Contents
1. EGFR
2. ALK
3. ROS1
4. B-RAF
5. MET
6. HER2
7. NTRK
8. SCLC
9. Complexities of the Lung Tumor Microenvironment
10. KRAS
11. Targeting Epigenetic Regulators in Cancer to Overcome Targeted Therapy Resistance.
2. ALK
3. ROS1
4. B-RAF
5. MET
6. HER2
7. NTRK
8. SCLC
9. Complexities of the Lung Tumor Microenvironment
10. KRAS
11. Targeting Epigenetic Regulators in Cancer to Overcome Targeted Therapy Resistance.