Autophagy : biology and diseases : basic science / Zheng-Hong Qin, editor.
Qin, Zheng-Hong.
2019
QH581.2
Available Online

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Title Autophagy : biology and diseases : basic science / Zheng-Hong Qin, editor.
ISBN 9789811506024 (electronic book)
9811506027 (electronic book)
9789811506017
Published Singapore : Springer, 2019.
Language English
Description 1 online resource (xv, 727 pages) : illustrations.
Other Standard Identifiers 10.1007/978-981-15-0
Call Number QH581.2
Dewey Decimal Classification 611.01816
Summary This book series consists of 3 volumes covering the basic science (Volume 1), clinical science (Volume 2) and the technology and methodology (Volume 3) of autophagy. Volume 1 focuses on the biology of autophagy, including the signaling pathways, regulating processes and biological functions. Autophagy is a fundamental physiological process in eukaryotic cells. It not only regulates normal cellular homeostasis, and organ development and function, but also plays an important role in the pathogenesis of a wide range of human diseases. Thanks to the rapid development of molecular biology and omic technologies, research on autophagy has boomed in recent decades, and more and more cellular and animal models and state-of the-art technologies are being used to shed light on the complexity of signaling networks involved in the autophagic process. Further, its involvement in biological functions and the pathogenesis of various diseases has attracted increased attention around the globe. Presenting cutting-edge knowledge, this book series is a useful reference resource for researchers and clinicians who are working on or interested in autophagy.
Access Note Access limited to authorized users.
Added Author Qin, Zheng-Hong.
Series Advances in experimental medicine and biology ; v. 1206.
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History and current status of autophagy research
Regulation of ATG and autophagy initiation
Regulation of autophagy by mTOR signaling pathway
AMPK and autophagy
Beclin 1, Bcl-2 and autophagy
TP53, TP53 target genes (DRAM, TIGAR) and autophagy
Ca(2+) ion and autophagy
Endoplasmic reticulum stress and autophagy
Oxidative stress and autophagy
Noncoding RNAs and atophagy
Epigenetic regulation of autophagy
Protein modification and autophagy activation
Other molecular mechanisms regulating Autophagy
The role of nanomaterials in autophagy
Structural basis of autophagy regulatory proteins
Autophagy and energy metabolism
Autophagy and lipid metabolism
Autophagy and the metabolism of misfolding protein
Autophagy in mitochondrial quality control
Chaperone-mediated autophagy
Autophagy in reproduction
Autophagy in development and differentiation
Autophagy in normal stem cells and specialized cells
Autophagy, aging and longevity
Autophagy and the ubiquitin-proteasome system
Immuno-signal and autophagy regulation
Autophagy and the immune response
Autophagy and immune tolerance
Autophagy and cell survival and death
Coordination of autophagy and other cellular activities.

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