Phytochemicals Targeting Tumor Microenvironment in Gastrointestinal Cancers / edited by Ganji Purnachandra Nagaraju.
Nagaraju, Ganji Purnachandra, editor.
2020
RC261-271
Available Online

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Title Phytochemicals Targeting Tumor Microenvironment in Gastrointestinal Cancers / edited by Ganji Purnachandra Nagaraju.
Edition 1st ed. 2020.
ISBN 9783030484057
303048405X
9783030484057
3030484041
9783030484040
DOI https://doi.org/10.1007/978-3-030-48405-7.
Published Cham : Springer International Publishing : Imprint: Springer, 2020.
Language English
Description 1 online resource (XI, 340 pages) :billustrations.
Other Standard Identifiers 10.1007/978-3-030-48405-7. doi
Call Number RC261-271
Dewey Decimal Classification 614.5999
Summary Gastrointestinal (GI) malignancies account for a large portion of cancers worldwide. Although incidence of esophageal, gastric, and colorectal cancers has decreased in recent years, pancreatic and liver cancer have increased. The mainstay of GI cancer therapy is chemoradiation and surgery. Despite significant medical advancements, diagnosis and therapy for GI cancers remain challenging due to tumor cell resistance to chemoradiotherapy. The tumor's increased cell signalling due to excessive transcription factor activation and increased stellate cell activity leads to collagen deposition formation of a dense stroma around the tumor, which prevents drugs from reaching the malignant cells. This leads to tumor chemoresistance. To circumvent these difficulties, drug therapy targeting the tumor's specific microenvironment and the additive anticancer effect of phytochemicals can allow for more effective treatment. This volume will be the first on the market on the topic of phytochemicals and their effect on the tumor microenvironment (TME). TME is an emerging area of research and the book will be a welcome introductory addition to the field.
Access Note Access limited to authorized users.
Added Author Nagaraju, Ganji Purnachandra, editor.
Available in Other Form Phytochemicals Targeting Tumor Microenvironment in Gastrointestinal Cancers
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All Resources
Role of specific phytochemicals against gastrointestinal malignancies
Role of phytochemicals on growth and metastasis of GI cancer
Cancer Stem Cells as Therapeutic Targets for Gastrointestinal cancers
Phytochemicals plus checkpoint inhibitors in GI cancers
Crucial role of curcumin on gut microbiota associated with GI cancers
Cellular and Molecular mechanisms of garlic compounds in common GI cancers
Combination of Phytochemicals with Nanotechnology for Targeting GI Cancer Therapy
Emerging Roles of Phytochemicals in the Pathobiology and Management of Esophageal Cancer
Gastric Cancer: Role of Phytochemicals and Tyrosine Kinase Inhibitors
Therapeutic Efects Of Curcumin Against Colorectal Cancer
Molecular Pathways Involved in the Pathogenesis of Pancreatic Cancer: Role of Phytochemicals in Targeting the Clinical Outcomes
Role of Dietary Supplementation of Natural products in the Prevention and Treatment of Liver Diseases
Emerging Roles of Phytochemicals in Hepatocellular Carcinoma
Phytochemicals: Current Understandings of the Modern Therapeutic Approaches for Hepatocellular Carcinoma
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