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Introduction
Thirty years of contrast enhanced breast MRI
The mantra about low specificity breast MRI
BRCA and other genes conferring hereditary breast cancer predisposition
Screening mammography: One size fits all?
MRI protocols for breast cancer screening
Contrast materials for screening MRI and concerns about tissue deposition
Applying MRI BI-RADS in a high-risk population
CAD systems for breast MRI screening
Phenotype presentation and radiogenomics of breast cancer with special focus on high-risk women
The body of primary evidence about MRI for high risk screening: retrospective and prospective studies
High-risk screening: MRI alone?
Secondary evidence from systematic reviews and meta-analyses
Radioprotection issues for women with hereditary predisposition for breast cancer
Impact of MRI screening on high-risk patient outcome
The special case of previous chest radiation therapy
IT infrastructure for data managing in multicenter high-risk screening
Guidelines and recommendations all over the world: agreements and differences
Medical options: Pharmacopreventio- Surgical options: Prophylactic mastectomy and oophorectomy
Psychosocial aspects of high-risk of breast cancer
Calculating, using and improving individual breast cancer risk estimates
MRI for screening women with a personal history of breast cancer
Screening MRI for the intermediate risk: an open issue
Looking at the future: Personalized breast cancer screening
Acknowledgments.

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