Macropinocytosis : functions and mechanisms / Cosimo Commisso, editor.
Commisso, Cosimo, editor.
2022
QH634 .M33 2022
Available Online

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Title Macropinocytosis : functions and mechanisms / Cosimo Commisso, editor.
ISBN 9783030940041 (electronic bk.)
3030940047 (electronic bk.)
9783030940034
3030940039
DOI https://doi.org/10.1007/978-3-030-94004-1
Published Cham : Springer, [2022]
Copyright ©2022
Language English
Description 1 online resource : color illustrations.
Item Number 10.1007/978-3-030-94004-1 doi
Call Number QH634 .M33 2022
Dewey Decimal Classification 571.6
Summary This book presents the functions and mechanisms of macropinocytosis, an actin-driven endocytic uptake process. Key points, including the evolutionary origins of macropinocytosis and major signaling pathways that regulate this uptake mechanism, are highlighted. A wide-array of functions of macropinocytosis are described, including cellular metabolism, cell death, cell migration and antigen presentation. Macropinocytosis has recently been recognized as a critical pathway in disease pathology and treatment. Therefore, a broad overview of macropinocytosis will benefit clinicians, as well as translational and basic research scientists. Moreover, as one of the main clathrin-independent endocytic routes, compiling all the critical information about macropinocytosis in one collection, this book will also be helpful to educators and their students.
Note Includes index.
Access Note Access limited to authorized users.
Source of Description Online resource; title from PDF title page (SpringerLink, viewed April 14, 2022).
Added Author Commisso, Cosimo, editor.
Series Sub-cellular biochemistry ; v. 98.
Available in Other Form Print version: 9783030940034
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Part 1: Functions of Macropinocytosis
Chapter 1: Functional Diversity of Macropinocytosis
Chapter 2: Macropinocytosis and Cancer: From Tumor Stress to Signaling Pathways
Chapter 3: The amoebal model for micropinocytosis
Chapter 4: Extracellular ATP and macropinocytosis
Chapter 5: Macropinocytosis and Cell Migration: Don't drink an drive
Chapter 6: Macropinocytosis in phagocyte function and immunity
Part 2: Signaling Mechanisms Driving Macropinocytosis
Chapter 7: Roles of 3' Phosphoinositides in Macropinocytosis
Chapter 8: Signaling pathways that regulate macropinocytosis in mammalian cells
Chapter 9: Wnt, GSK3 and Macropinocytosis
Chapter 10: Kras addiction promotes cancer cell adapation in harsh microenvironment through micropinocytosis
Chapter 11: Kras-independent macropinocytosis in pancreatic cancer.

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