Progress in the chemistry of organic natural products. Volume 115 / A. Douglas Kinghorn, Heinz Falk, Simon Gibbons, Yoshinori Asakawa, Ji-Kai Liu, Verena M. Dirsch, editors.
Kinghorn, A. Douglas.; Falk, Heinz, 1939-; Gibbons, Simon (Professor of medicinal phytochemistry); Asakawa, Yoshinori.; Liu, Ji-Kai.; Dirsch, Verena M.
2021
QD251 .P76 2021
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Title Progress in the chemistry of organic natural products. Volume 115 / A. Douglas Kinghorn, Heinz Falk, Simon Gibbons, Yoshinori Asakawa, Ji-Kai Liu, Verena M. Dirsch, editors.
ISBN 9783030648534 (electronic bk.)
3030648532 (electronic bk.)
9783030648527
3030648524
DOI https://doi.org/10.1007/978-3-030-64853-4
Published Cham : Springer, 2021.
Language English
Description 1 online resource (210 pages)
Item Number 10.1007/978-3-030-64853-4 doi
Call Number QD251 .P76 2021
Dewey Decimal Classification 547
Summary This book describes current understandings and recent progress into a varied group of natural products. In the first chapter the role that total synthesis may play in revising the structures proposed for decanolides, which are ten-membered lactones found primarily in fungi, frogs, and termites is presented. The following chapter presents the development of the intriguing plant-derived sesquiterpene lactone, thapsigargin, a potent inhibitor of the enzyme, SERCA (sarco-endoplasmic Ca2+ ATPase), which has potential as a lead compound to treat cancer. The third chapter covers the potential of various plant phenolic compounds for treating the tropical and sub-tropical infectious disease, leishmaniasis. In addition the volume presents recent advances related to the plant alkaloid, cryptolepine, which is of particular interest as a lead for the treatment of malaria, trypanosomiasis, and cancer.
Access Note Access limited to authorized users.
Source of Description Description based on print version record.
Added Author Kinghorn, A. Douglas.
Falk, Heinz, 1939-
Gibbons, Simon (Professor of medicinal phytochemistry)
Asakawa, Yoshinori.
Liu, Ji-Kai.
Dirsch, Verena M.
Series Progress in the chemistry of organic natural products (2011) ; 115.
Available in Other Form Progress in the Chemistry of Organic Natural Products 115.
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Total Synthesis of Decanolides (Nonanolides) with a Special Focus on Olefin Metathesis
From Plant to Patient: Thapsigargin
Antileishmanial Activity of Lignans and Neolignans
Cryptolepine as a Lead to new Antiprotozoal Agents
Biologically Active Constituents from Plants of the Genus Xanthium.

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